Κυριακή 14 Μαρτίου 2010

Difference between Diabetes Inipidus and Diabetes Mellitus

Diabetes Insipidus is a result of other pituitary not secreting enough vasopressin or kidneys not responding to vasopressin. This has as a consequence excessive water secretion, as water cannot be reabsorbed. Usually polyuria is sudden, polydipsia and dehydration are also symptoms of Diabetes Insipidus. If it is Central Diabetes Insipidus, then desmopressin is recommended as a tretment. In Nephrogenic Diabetes Insipidus a low sodium intake is recommende and treatment includes the concomintant use of thiazide and potassium-sparing diuretics.
Diabetes Mellitus is associated to insulin. In Type 1 Diabetes, there not enough insulin being secreted, whereas in type 2 insulin is present but cells fail to respond to it. Type 1 Diabetics are treated with insulin replacement, whereas type 2are treated by Oral sulfonylureas (like glimepiride, glyburide, and tolazamide), Biguanides (Metformin), Alpha-glucosidase inhibitors (such as acarbose),Thiazolidinediones (such as rosiglitazone) and Meglitinides (including repaglinide and nateglinide. Metformin is usually the treatment of choice. As for the symptoms present in Diabetes Mellitus include polyuria, polydipsia, polyphagia, weight changes, tiredness and skin infections.

http://www.diabetesinsipidus.org/4di_di_vs_dm.htm

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