Τρίτη 5 Ιανουαρίου 2010

Wernicke-Korsakov syndrome

Detoxification may precipitate Wernicke’s encephalopathy, which must be treated urgently with parenteral thiamine. There is a very small risk of anaphylaxis with parenteral vitamin supplementation. This is less likely with the intramuscular route. There has been one case of anaphylaxis solely attributable to intramuscular Pabrinex since 1996.

Symptoms

◦confusion
◦ataxia, especially truncal ataxia
◦ophthalmoplegia
◦nystagmus
◦memory disturbance
◦hypothermia and hypotension
◦coma


http://www.sign.ac.uk/guidelines/fulltext/74/section4.html

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